Making use of single-molecule optical and AFM imaging and drive-spectroscopy tactics, we seek out to unravel the mechanistic elements of the composition and dynamics of chromosomes. Our exploration passions consist of:

Our group studies bacterial mobile division which is aiming to constitute a ‘bottom up biology’ in artificial cells which can autonomously divide. Our principal curiosity lies in cell division, chromatin composition, and spatial Regulate.

[Laughs] ‘It had been absolutely a terrific chance! At enough time, I used to be nicely conscious that it could go wrong and that I could become significantly less prosperous, but I just overlooked that. Curiosity has constantly been my strongest driving power. And luckily everything labored out.’

Our work was rapidly followed up by Other people, most notably by Phaedon Avouris and colleagues at IBM, who in October 1998 revealed their results on transistors made out of solitary- and multi-walled carbon nanotubes in Utilized Physics Letters.

That may be a desire of mine and we set to operate having a delectable dose of naivety. This can be a thing that will probably produce impressive results in the more time time period, but that does not make a difference. You shouldn't only want to operate around the issues of tomorrow, but also within the issues from the day just after tomorrow.’

Our exploration ranges with the biophysics of DNA to artificial cells and outside of. You should take a look under on the spectrum of our existing initiatives.

Numerous associated developments followed, in which our group set up distinct transistor variants for example solitary-electron transistors at area temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled many transistors into smaller evidence-of-theory electronic circuits.

Dynamic ParB–DNA interactions initiate and sustain a partition condensate for bacterial chromosome segregation

In 1993, as a young and keen affiliate professor at Delft College of Technologies, I'd in the beginning focused the analysis initiatives of my team on measuring the electrical conductance of a single conducting-polymer molecule. Within just two years, we had developed a tool wherein a single wire of a phthalocyaninepolysiloxane polymer was linked involving two intently spaced metal nanoelectrodes.

‘The fantastically delicate way by which components in mother nature functionality under no circumstances ceases to amaze me. If we fix the puzzle of how existence came into remaining, I be expecting that my amazement with the complexity of creation will have amplified and with it my awe for that greatness in the Creator.’

[14] In 2005 Dekker grew to become involved in Netherlands-extensive conversations about Smart Structure, a movement that he has considering the fact that Obviously distanced himself from. Dekker advocates that science and faith usually are not in opposition but is usually harmonized.

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For example, we think about the nucleopore advanced, a gateway involving the cell nucleus and also the cytoplasm. This is a very sophisticated process and for that ceesdekker reason challenging to review in the cell, so we use biomimetics. We reconstruct holes and then insert unique things in the nucleopore complicated to check transport by means of it at the single-molecule stage.’

‘I am driven by ponder and thoughts. On a material level I locate solutions in physics, but I working experience my deepest happiness with God. That faith also drives my science and how I take care of persons.